Detalhe da pesquisa
1.
Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice.
Immunity
; 55(11): 2168-2186.e6, 2022 11 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36179690
2.
Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity
; 55(11): 2149-2167.e9, 2022 11 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36179689
3.
HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage.
Immunity
; 47(5): 990-1003.e9, 2017 11 21.
Artigo
Inglês
| MEDLINE | ID: mdl-29166592
4.
Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows.
Nature
; 548(7665): 108-111, 2017 08 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28726771
5.
Visualization of the HIV-1 Env glycan shield across scales.
Proc Natl Acad Sci U S A
; 117(45): 28014-28025, 2020 11 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33093196
6.
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
PLoS Pathog
; 16(8): e1008665, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32780770
7.
EMHP: an accurate automated hole masking algorithm for single-particle cryo-EM image processing.
Bioinformatics
; 33(23): 3824-3826, 2017 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28961740
8.
Nonequilibrium dynamics and ultraslow relaxation of confined DNA during viral packaging.
Proc Natl Acad Sci U S A
; 111(23): 8345-50, 2014 Jun 10.
Artigo
Inglês
| MEDLINE | ID: mdl-24912187
9.
Continuous allosteric regulation of a viral packaging motor by a sensor that detects the density and conformation of packaged DNA.
Biophys J
; 108(2): 315-24, 2015 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-25606680
10.
Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.
Nat Commun
; 13(1): 5236, 2022 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36068229
11.
Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun
; 12(1): 4817, 2021 08 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34376662
12.
Quantification of the Resilience and Vulnerability of HIV-1 Native Glycan Shield at Atomistic Detail.
iScience
; 23(12): 101836, 2020 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-33319171
13.
Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv
; 6(22): eaba0468, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32518821
14.
Vulnerabilities in coronavirus glycan shields despite extensive glycosylation.
Nat Commun
; 11(1): 2688, 2020 05 27.
Artigo
Inglês
| MEDLINE | ID: mdl-32461612
15.
HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies.
Cell Rep
; 31(4): 107583, 2020 04 28.
Artigo
Inglês
| MEDLINE | ID: mdl-32348769
16.
Differences in the Binding Affinity of an HIV-1 V2 Apex-Specific Antibody for the SIVsmm/mac Envelope Glycoprotein Uncouple Antibody-Dependent Cellular Cytotoxicity from Neutralization.
mBio
; 10(4)2019 07 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31266872
17.
Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle.
Nat Commun
; 10(1): 4272, 2019 09 19.
Artigo
Inglês
| MEDLINE | ID: mdl-31537780
18.
Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep
; 23(11): 3249-3261, 2018 06 12.
Artigo
Inglês
| MEDLINE | ID: mdl-29898396
19.
Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer.
Nat Commun
; 9(1): 3693, 2018 09 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30209313
20.
Experimental comparison of forces resisting viral DNA packaging and driving DNA ejection.
Phys Rev E
; 95(5-1): 052408, 2017 May.
Artigo
Inglês
| MEDLINE | ID: mdl-28618627